The North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD) was established in 2006 as the North American regional representative of the International epidemiology Databases to Evaluate AIDS (IeDEA). Comprised of more than 20 classical and clinical collaborating cohorts, NA-ACCORD is designed to be widely representative of adults in HIV care in the United States and Canada. Over 200 sites contribute data on over 190,000 HIV-infected participants.

NA-ACCORD has a multi-disciplinary group of collaborators that span disciplines such as basic science, clinical research, epidemiology, data informatics and biostatistics. Collectively, our group is poised to frame, design, and successfully answer key questions about the epidemiology of the HIV epidemic, as well as HIV treatment and clinical care. The NA-ACCORD has established a unique scientific platform to address clinical issues that are now of paramount importance in the modern treatment era.

The goals of NA-ACCORD are:

1. To characterize the clinical course of HIV infection in North America, with a focus on aging, non-AIDS comorbidities and life expectancy.
2. To characterize and extend the HIV Care Continuum in North America beginning at engagement in HIV care through viral suppression and beyond. Utilizing the substantial individual-level longitudinal data available from across North America.
3. To characterize the impact of new direct-acting antivirals (DAAs) on hepatitis C (HCV) disease in HIV-HCV co-infected persons.
4. To develop and apply novel statistical and epidemiological methodology that is applicable to these scientific research initiatives.
5. To collaborate with other regional cohorts of IeDEA to compare results and address questions of inter-regional importance.